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Current US Trials :

Vaccine Therapy Combined With Interleukin-2 and Interferon alfa in Treating Patients With Metastatic Renal Cell Carcinoma (Kidney Cancer) (Contact: Dr. Marc Stuart Ernstoff, Dartmouth Medical School, Lebanon, New Hampshire, 03756)

Vaccine Therapy in Treating Patients With Malignant Glioma
(Contact: Dr. Linda M. Liau, UCLA, Los Angeles, CA, 90095)

Vaccine Therapy in Treating Patients With Liver Cancer
(Contact: Dr. Antoni Ribas UCLA, Los Angeles, CA, 90095)

Chemotherapy Followed By Vaccine Therapy in Treating Patients With Extensive-Stage Small Cell Lung Cancer (Contact: Scott Antonia, H. Lee Moffitt Cancer Center and Research Institute, Tampa, FL 33612)

Therapy for Colorectal Cancer
(Contact: NCI, Bethesda, MD 20892; E-mail: ncicssc@mail.nih.gov)

Study of Tumor Antigen-Pulsed Autologous Dendritic Cell Vaccination Administrated Subcutaneously or Intranodally (Contact: Mark A Mosby, U. of Arkansas for Medical Sciences, Little Rock, Arkansas)

A Safety and Feasibility Study of Active Immunotherapy in Patients with Metastatic Prostate Carcinoma Using Autologous Dendritic Cells Pulsed with Antigen Encoded in Amplified Autologous Tumor RNA
(Contact: Doris M. Coleman, Duke University Medical Center, Durham, North Carolina)

PROvenge Trial
(Multiple sites throughout the US) for early stage prostate cancer patients who have undergone a radical prostatectomy and whose only sign of disease recurrence is a rise in serum PSA.

Tumor Lysate Pulsed-Dendritic Cell Vaccines after High-Dose Chemotherapy for Non-Hodgkin's Lymphoma

Safety and tolerability of a patient's own dendritic cells combined with a new compound (KRN7000) in patients with advanced cancer
(Principal Investigator: Dr. Keren Osman, Rockerfeller University, New York )

Evaluation of the Effects of Local GM-CSF-in-adjuvant Administration on Dendritic Cells in Skin of Melanoma Patients and in Sentinel Lymph Nodes
(Contact: Lori Elder, U. of Virginia Medical School, Charlottesville, VA)

A Phase I/II Trial of Vaccination with Dendritophage (Df) Pulsed with Multiple Peptides in the Treatment of HLA-A2 Positive Patients with Metastatic Colorectal Cancer (Contact: City of Hope National Medical Center, 1500 East Duarte Road, Duarte, CA 91010-3000)

A Randomized, Double Blind, Placebo Controlled Trial of Immunotherapy with Autologous Antigen-Loaded Dendritic Cells For Asymptomatic Metastatic Hormone Refractory Prostate Cancer. (Contact: Nicole Zampardi, Study Coordinator Staten Island Urological Research, P.C. 1800 Clove Road, Staten Island, NY)

Vaccine Therapy With Either Neoadjuvant or Adjuvant Chemotherapy and Adjuvant Radiation Therapy in Treating Women With p53-Overexpressing Stage II or Stage III Breast Cancer (Contact: Dr. Elizabeth Reed, Eppley Cancer Center at the University of Nebraska Medical Center, Omaha, Nebraska, 68198)

Vaccine Therapy in Treating Patients With Advanced or Metastatic Cancer expressing CEA (Contact: Herbert Kim Lyerly Duke Comprehensive Cancer Center, Durham, NC)

Vaccine Therapy in Treating HLA-A201 Positive Patients With Refractory CEA Expressing Stage IV Cancer (Contact: Herbert Kim Lyerly Duke Comprehensive Cancer Center, Durham, NC)

Vaccine Therapy in Treating Patients With Stage III or Stage IV Melanoma
(contact: Gerold Schuler, Dermatologische Klinik MIT Poliklinik-Universitaetsklinikum Erlangen, Erlangen, D-91052, Germany)