Dendritic
Cell (DC) therapy represents a new and promising
immunotherapeutic approach for treatment
of advance cancer as well as for secondary
prevention of cancer. As Dr. Harmon Eyre,
the VP of Research at the AMA commented on results
of DC therapy for cancer: “Patients' responses
are far out of proportion to anything that
any current therapy could do”. For decades,
cancer researchers have been interested
in immunologic treatment using vaccines
against cancer but with little progress.
However, recent advances in recognition
of the importance of 1) tumor associated
antigens that can be used to vaccinate patients,
and 2) the dendritic cell as a potent blood
cell to present such antigens and stimulate
the naïve immune system together leads
to successful implementation of Dendritic Cell therapy
with reports of complete responses even
in stage IV cancer patients who have failed
all other therapies. Dendritic Cell (DC) Therapy or so-called Dendritic Cell vaccine is a newly emerging and potent form of immune therapy used to treat cancer, AIDS and other serious conditions. In case of cancer, Dendritic Cell therapy is an immune therapy which harnesses the body's own immune system to fight cancer. The Dendritic Cell itself is an immune cell whose role is the recognition, processing and presentation of foreign antigens to the T-cells in the effector arm of the immune system. Although Dendritic Cells are potent cells, they are not usually present in adequate quantity to allow for a potent immune response. Dendritic Cell Therapy thus involves the harvesting of blood cells (ie monocytes or macrophages) from a patient and processing them in the laboratory to produce Dendritic Cells which are then given back to a patient in order to allow massive Dendritic participation in optimally activating the immune system. To learn more about vaccine and Dendritic Cell therapy for cancer, please read the following: